2018年9月18日星期二

GSK3B (Ser9) Antibody

Product  GSK3B (Ser9) Antibody
Cat#  100-32-54A
Unit/Weight  100 μg
Unit Price  $381.00
Species Reactivity  B, Ck, D, Mk, M, X, Zf
Tested Application(s)  E, WB
Brief Description  Phosphospecific Antibody, Rabbit Polyclonal Antibody
Specific Description  Glycogen synthase kinase-3 beta (GSK3b) participates in the Wnt signaling pathway. GSK3b is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor Jun. GSK3b phosphorylates Jun at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Ser9 phosphorylation underlies the inhibition of GSK3b by insulin. This antibody is specific for the 46-kDa GSK-3b protein phosphorylated at Ser9, however a band at 51-kDa can also be detected due to high homology with GSK-3 alpha.
Storage  Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

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