2018年9月18日星期二

Peptide-binding specificity of the molecular chaperone BiP

Peptide-binding specificity of the molecular chaperone BiP

GC Flynn, J Pohl, MT Flocco, JE Rothman - Nature, 1991 - nature.com
Members of the heat-shock protein family (hsp70s) can distinguish folded from unfolded
proteins. This property is crucial to the role of hsp70s as molecular chaperones and is
attributable to the amino-acid specificity of the peptide-binding site. The specificity for …

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