Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

L Zitvogel, JI Mayordomo, T Tjandrawan… - Journal of …, 1996 - jem.rupress.org

Antigen presentation by host dendritic cells (DC) is critical for the initiation of adaptive
immune responses. We have previously demonstrated in immunogenic murine tumor
models that bone marrow (BM)-derived DC pulsed ex vivo with synthetic tumor-associated …