2018年9月18日星期二

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

CF Deacon, AH Johnsen, JJ Holst - The Journal of Clinical …, 1995 - academic.oup.com
The metabolism of glucagon-like peptide-1 (GLP-1) has not been studied in detail, but it is
known to be rapidly cleared from the circulation. Measurement by RIA is hampered by the
fact that most antisera are side-viewing or C-terminally directed, and recognize both intact …

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