2018年10月10日星期三

A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction

A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction

TE Speltz, JM Danes, JD Stender, J Frasor… - ACS chemical …, 2018 - ACS Publications
We and others have proposed that coactivator binding inhibitors, which block the interaction
of estrogen receptor and steroid receptor coactivators, may represent a potential class of
new breast cancer therapeutics. The development of coactivator binding inhibitors has been …


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