2018年10月23日星期二

An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies

An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies

J Seo, W Hoffmann, S Warnke, X Huang, S Gewinner… - Nature …, 2017 - nature.com
Amyloidogenic peptides and proteins play a crucial role in a variety of neurodegenerative
disorders such as Alzheimer's and Parkinson's disease. These proteins undergo a
spontaneous transition from a soluble, often partially folded form, into insoluble amyloid …


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