2018年10月17日星期三

Design and synthesis of a luminescent iridium complex-peptide hybrid (IPH) that detects cancer cells and induces their apoptosis

Design and synthesis of a luminescent iridium complex-peptide hybrid (IPH) that detects cancer cells and induces their apoptosis

AA Masum, K Yokoi, Y Hisamatsu, K Naito… - Bioorganic & medicinal …, 2018 - Elsevier
Tumor necrosis factor related apoptosis inducing ligand (TRAIL) triggers the cell-extrinsic
apoptosis pathway by complexation with its signaling receptors such as death receptors
(DR4 and DR5). TRAIL is a C 3-symmetric type II transmembrane protein, consists of three …


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