2018年10月22日星期一

IKK epsilon Antibody

Product  IKK epsilon Antibody
Cat#  100-21-55A
Unit/Weight  100 μg
Unit Price  $311.00
Species Reactivity  H
Tested Application(s)  E, WB, IHC
Brief Description  (CT) IkB Kinase epsilon
Specific Description  Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A novel molecule in the IKK complex was recently identified and designated IKKepsilon/IKK-i (1,2). IKK epsilon is required for the activation of NF-kappaB by PMA and T cell receptors but not by TNFalpha and IL-1 (1). IKKepsilon/IKK-i message is expressed in a variety of tissues and is inducible by TNFalpha, IL-1, and LPS (2).
Storage  IKK epsilon antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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