2018年10月11日星期四

Suppression of circadian secretion of glucagon‐like peptide‐1 by the saturated fatty acid, palmitate

Suppression of circadian secretion of glucagon‐like peptide‐1 by the saturated fatty acid, palmitate

A Martchenko, RH Oh, SE Wheeler, P Gurges… - Acta …, 2018 - Wiley Online Library
Aim Glucagon‐like peptide‐1 is an incretin hormone secreted by the intestinal L‐cell with a
circadian rhythm that parallels expression of the core clock gene, Bmal1. Although feeding
rats a high‐fat/high‐sucrose Western diet impairs rhythmic glucagon‐like peptide‐1 release …

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