Using transgenic MHC class II/self-peptide reactive cytotoxic T cells as a method of ameliorating established EAE
JR Lees, S Nurmukhambetova, YC Kim, AH Zhang… - 2017 - Am Assoc Immnol
In multiple sclerosis (MS) CD4+ T cells are thought to coordinate initiation and maintenance
of neuroinflammation following recognition of central nervous system (CNS) antigens in the
context of MHC class II molecules. Re-activation of these CNS antigen specific CD4+ T cells …
of neuroinflammation following recognition of central nervous system (CNS) antigens in the
context of MHC class II molecules. Re-activation of these CNS antigen specific CD4+ T cells …
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