Glucagon-like peptide-1 and its class BG protein–coupled receptors: a long march to therapeutic successes

Glucagon-like peptide-1 and its class BG protein–coupled receptors: a long march to therapeutic successes

C De Graaf, D Donnelly, D Wootten, J Lau… - Pharmacological …, 2016 - ASPET

The glucagon-like peptide (GLP)-1 receptor (GLP-1R) is a class BG protein–coupled
receptor (GPCR) that mediates the action of GLP-1, a peptide hormone secreted from three
major tissues in humans, enteroendocrine L cells in the distal intestine, α cells in the …

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