2018年11月25日星期日

PIG-Y Antibody

Product  PIG-Y Antibody
Cat#  100-11-89A
Unit/Weight  100 μg
Unit Price  $311.00
Species Reactivity  H, M
Tested Application(s)  E, WB, IHC
Brief Description  (IN) Phosphatidylinositol glycan anchor Pepmic class Y
Specific Description  Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the Pepmic of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA. This antibody only detects isoform 1 of PIG-Y. Despite its predicted molecular weight, PIG-Y often migrates at 28-30 kDa in SDS-PAGE.
Storage  PIG-Y antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures

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