Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase

Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase

JM Reimer, MN Aloise, PM Harrison, TM Schmeing - Nature, 2016 - nature.com

Nonribosomal peptide synthetases (NRPSs) are very large proteins that produce small
peptide molecules with wide-ranging biological activities, including environmentally friendly
chemicals and many widely used therapeutics 1. NRPSs are macromolecular machines …

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