A role for 4‐hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β‐peptide
RJ Mark, MA Lovell, WR Markesbery… - Journal of …, 1997 - Wiley Online Library
Abstract: Peroxidation of membrane lipids results in release of the aldehyde 4-
hydroxynonenal (HNE), which is known to conjugate to specific amino acids of proteins and
may alter their function. Because accumulating data indicate that free radicals mediate injury
hydroxynonenal (HNE), which is known to conjugate to specific amino acids of proteins and
may alter their function. Because accumulating data indicate that free radicals mediate injury
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