Penicillin: its basic site of action as an inhibitor of a peptide cross-linking reaction in cell wall mucopeptide synthesis
EM Wise, JT Park - Proceedings of the National Academy of …, 1965 - National Acad Sciences
It has been known for some time that penicillin interferes with bacterial cell wall mucopeptide
synthesis. 1-'When a penicillin-sensitive cell grows in the presence of penicillin, the integrity
of the cell wall is lost and the cell either ruptures or its membrane is damaged beyond repair.
synthesis. 1-'When a penicillin-sensitive cell grows in the presence of penicillin, the integrity
of the cell wall is lost and the cell either ruptures or its membrane is damaged beyond repair.
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