[HTML] Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
J Yang, MS Brown, G Liang, NV Grishin, JL Goldstein - Cell, 2008 - Elsevier
Ghrelin is a 28 amino acid, appetite-stimulating peptide hormone secreted by the food-
deprived stomach. Serine-3 of ghrelin is acylated with an eight-carbon fatty acid, octanoate,
which is required for its endocrine actions. Here, we identify GOAT (Ghrelin O-
deprived stomach. Serine-3 of ghrelin is acylated with an eight-carbon fatty acid, octanoate,
which is required for its endocrine actions. Here, we identify GOAT (Ghrelin O-
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