[HTML] A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases

[HTML] A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases

CG Knight, F Willenbrock, G Murphy - FEBS letters, 1992 - Elsevier

Abstract (7-methoxycoumarin-4-yl) Acetyl-Pro-Leu-Gly-Leu-(3-[2, 4-dinitrophenyl]-l-2, 3-
diaminopropionyl)-Ala-Arg-NH 2 (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH 2) has been
synthesised as a fluorogenic substrate for the matrix metalloproteinases. The highly

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