2018年1月3日星期三

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

AA Vandenbark, G Hashim, H Offner - Nature, 1989 - Springer
Abstract T CELLS expressing the αβ T-cell receptor (TCR) for antigen can elicit anti-idiotypic
antibodies specific for the TCR that regulate T-cell function 1–4. Defined sequences of the
TCR, however, have not been used to elicit specific antibodies and the role of cellular


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