2018年9月1日星期六

A D‐Peptide Ligand of Nicotine Acetylcholine Receptors for Brain‐Targeted Drug Delivery

DPeptide Ligand of Nicotine Acetylcholine Receptors for Brain‐Targeted Drug Delivery

X WeiC Zhan, Q Shen, W Fu, C Xie, J Gao… - Angewandte …, 2015 - Wiley Online Library
Lysosomes of brain capillary endothelial cells are implicated in nicotine acetylcholine
receptor (nAChR)‐mediated transcytosis and act as an enzymatic barrier for the transport of
peptide ligands to the brain. A d‐peptide ligand of nAChRs (termed DCDX), which binds to …


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