2018年9月1日星期六

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

K Haslinger, M Peschke, C Brieke, E Maximowitsch… - Nature, 2015 - nature.com
Non-ribosomal peptide synthetase (NRPS) mega-enzyme complexes are modular assembly
lines that are involved in the biosynthesis of numerous peptide metabolites independently of
the ribosome 1. The multiple interactions between catalytic domains within the NRPS …


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