2018年10月11日星期四

Antigen Presentation: Visualizing the MHC Class I Peptide-Loading Bottleneck

Antigen Presentation: Visualizing the MHC Class I Peptide-Loading Bottleneck

M Lamers, I BerlinJ Neefjes - Current Biology, 2018 - cell.com
The peptide-loading complex is a bottleneck in antigen presentation by major
histocompatibility complex (MHC) class I molecules. While the structures of its individual
components were known, the recent report of the 7.2 Å structure of the entire complex now …

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