Structure-guided design of a potent peptide inhibitor targeting the interaction between CRK and ABL kinase
Q Shen, VS Bhatt, I Krieger, JC Sacchettini, JH Cho - MedChemComm, 2018 - pubs.rsc.org
CT-10 regulator of kinase (CRK) proteins play important roles in human cancer metastasis
and invasion. Moreover, CRK proteins are the major phosphorylation substrates of ABL
kinase and its oncogenic mutant BCR-ABL kinase. The interaction between CRK and BCR …
and invasion. Moreover, CRK proteins are the major phosphorylation substrates of ABL
kinase and its oncogenic mutant BCR-ABL kinase. The interaction between CRK and BCR …
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