[HTML] Inflammatory-linked changes in CpG island methylation of three opioid peptide genes in a rat model for pain

[HTML] Inflammatory-linked changes in CpG island methylation of three opioid peptide genes in a rat model for pain

CLJ Jacobi, C Stein - PloS one, 2018 - journals.plos.org

Expression of the opioid peptide genes proopiomelanocortin (Pomc), proenkephalin (Penk),
and prodynorphin (Pdyn), in immune cells plays a key role in endogenous pain control. In a
rat model of painful unilateral paw inflammation, we isolated cells from popliteal lymph …

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