2018年10月22日星期一

Inhibiting Epidermal Growth Factor Receptor Dimerization and Signaling Through Targeted Delivery of a Juxtamembrane Domain Peptide Mimic

Inhibiting Epidermal Growth Factor Receptor Dimerization and Signaling Through Targeted Delivery of a Juxtamembrane Domain Peptide Mimic

J Gerhart, AF Thévenin, E Bloch, KE King… - ACS chemical …, 2018 - ACS Publications
Overexpression and deregulation of the epidermal growth factor receptor (EGFR) are
implicated in multiple human cancers and therefore are a focus for the development of
therapeutics. Current strategies aimed at inhibiting EGFR activity include monoclonal …


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