Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway

Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway

C Guo, E Rosoha, MB Lowry, N Borregaard… - The Journal of nutritional …, 2013 - Elsevier

The vitamin D receptor (VDR) mediates the pleiotropic biologic effects of 1α, 25 dihydroxy-
vitamin D 3. Recent in vitro studies suggested that curcumin and polyunsaturated fatty acids
(PUFAs) also bind to VDR with low affinity. As potential ligands for the VDR, we …

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