Synthesis of water-soluble scaffolds for peptide cyclization, labeling, and ligation

Synthesis of water-soluble scaffolds for peptide cyclization, labeling, and ligation

LEJ Smeenk, N Dailly, H Hiemstra… - Organic …, 2012 - ACS Publications

The synthesis and applications of water-soluble scaffolds that conformationally constrain
side chain unprotected linear peptides containing two cysteines are described. These
scaffolds contain a functionality with orthogonal reactivity to be used for labeling and …

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