2019年1月29日星期二

Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide

Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide

WG Forssmann, M Stoll, K Adermann… - Science translational …, 2010 - stm.sciencemag.org
To infect host cells, most enveloped viruses must insert a hydrophobic fusion peptide into
the host cell membrane. Thus, fusion peptides may be valuable targets for developing drugs
that block virus entry. We have shown previously that a natural 20-residue fragment of α 1 …


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