Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction with improved binding and cellular activity

Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction with improved binding and cellular activity

R Hancock, M Schaap, H Pfister, G Wells - Organic & biomolecular …, 2013 - pubs.rsc.org

Inhibitors of the Keap1–Nrf2 protein–protein interaction (PPI) have been proposed as
potential anti-inflammatory and cancer chemopreventive agents. Such compounds have the
potential to increase the intracellular concentrations of Nrf2 in a reversible manner and …

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