2019年1月30日星期三

Ectodomain shedding and remnant peptide signalling of EGFRs and their ligands

Ectodomain shedding and remnant peptide signalling of EGFRs and their ligands

S Higashiyama, D Nanba, H Nakayama… - The Journal of …, 2011 - academic.oup.com
Both receptor tyrosine kinases epidermal growth factor receptors (EGFRs) and their ligands
are transmembrane proteins. It has been known that ligand binding activates cytoplasmic
tyrosine kinase domains of EGFRs, resulting in the transduction of signals for cell …


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