Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library

Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library

U Jüse, Y van de Wal, F Koning, LM Sollid… - Human immunology, 2010 - Elsevier

Human leukocyte antigen (HLA)-DQ2 (DQA1× 0501/DQB1× 0201) is associated with
several immune disorders, including celiac disease, which is caused by an inappropriate T-
cell response to gluten. Interference with peptide presentation by HLA-DQ2, for example, by …

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