HTML] Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

HTML] Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

S El Andaloussi, T Lehto, I Mäger… - Nucleic acids …, 2011 - academic.oup.com

While small interfering RNAs (siRNAs) have been rapidly appreciated to silence genes,
efficient and non-toxic vectors for primary cells and for systemic in vivo delivery are lacking.
Several siRNA-delivery vehicles, including cell-penetrating peptides (CPPs), have been …

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