Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets

Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets

H Chu, M Pazgier, G Jung, SP Nuccio… - …, 2012 - science.sciencemag.org

Defensins are antimicrobial peptides that contribute broadly to innate immunity, including
protection of mucosal tissues. Human α-defensin (HD) 6 is highly expressed by secretory
Paneth cells of the small intestine. However, in contrast to the other defensins, it lacks …

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