Mimicry of high-density lipoprotein: functional peptide–lipid nanoparticles based on multivalent peptide constructs

Mimicry of high-density lipoprotein: functional peptide–lipid nanoparticles based on multivalent peptide constructs

Y Zhao, T Imura, LJ Leman, LK Curtiss… - Journal of the …, 2013 - ACS Publications

We describe an approach for engineering peptide–lipid nanoparticles that function similarly
to high-density lipoprotein (HDL). Branched, multivalent constructs, bearing multiple 23-or
16-amino-acid peptides, were designed, synthesized, and combined with phospholipids to …

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