Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule

Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule

M Rasmussen, M Harndahl, A Stryhn… - The Journal of …, 2014 - Am Assoc Immnol

MHC class I molecules (HLA-I in humans) present peptides derived from endogenous
proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and-B molecules have
been studied extensively, little is known about HLA-C specificities. Combining a positional …

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