AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies

AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies

K Yamada, N Shikida, K Shimbo, Y Ito… - Angewandte Chemie …, 2019 - Wiley Online Library

The need for atom precise biomolecule modification, and particularly the irreversible
formation of covalent bonds to specific amino acids in proteins, has become an essential
issue in the fields of pharmaceuticals and chemical biology. For examples, antibody–drug …

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