2019年4月11日星期四

HTML] Peptide-based PET quantifies target engagement of PD-L1 therapeutics

HTML] Peptide-based PET quantifies target engagement of PD-L1 therapeutics

D Kumar, A Lisok, E Dahmane… - The Journal of …, 2019 - Am Soc Clin Investig
Immune checkpoint therapies have shown tremendous promise in cancer therapy. However,
tools to assess their target engagement, and hence the ability to predict their efficacy, have
been lacking. Here, we show that target engagement and tumor-residence kinetics of …


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