2019年4月21日星期日

[HTML] Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

[HTML] Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

KT O'Brien, K Golla, T Kranjc, D O'Donovan, S Allen… - PloS one, 2019 - journals.plos.org
Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs)
represent potential targets. Focal adhesions play a central role in adhesion by linking cells
to the extracellular matrix. Integrins are central to this process, and many other intracellular …


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