2019年4月11日星期四

Photo-Control of Small GTPase RAS GDP-GTP Exchange Reaction using Novel Peptide Inhibitor Modified with Azobenzene Derivatives

Photo-Control of Small GTPase RAS GDP-GTP Exchange Reaction using Novel Peptide Inhibitor Modified with Azobenzene Derivatives

N Nishibe, M Kuboyama, K Taii, T Nagashima… - Biophysical …, 2019 - cell.com
Previously we have demonstrated that guanine nucleotide exchange activity of SOS for
small G protein Ras is photoreversibly controlled by the peptide mimicking SOSαH helix
region, which is modified with azobenzene-di-maleimide (ABDM). Recently, a novel peptide  …


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