Peptide-mediated delivery of rna-guided endonuclease into cells

Peptide-mediated delivery of rna-guided endonuclease into cells

RL Frisch, X Fan, SP Hong… - US Patent App. 16/218,808, 2019 - Google Patents

A composition is disclosed that comprises at least one protein component of an RNA-guided
endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN
protein component and CPP are covalently or non-covalently linked to each other in an …

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