Synthesis and biological evaluation of phthalocyanine-peptide conjugate for EGFR-targeted photodynamic therapy and bioimaging

Synthesis and biological evaluation of phthalocyanine-peptide conjugate for EGFR-targeted photodynamic therapy and bioimaging

L Yu, Q Wang, RCH Wong, S Zhao, DKP Ng, PC Lo - Dyes and Pigments, 2019 - Elsevier

To improve the biocompatibility and tumor selectivity, we employed an epidermal growth
factor receptor (EGFR) binding peptide (namely GE11, with a sequence of Tyr-His-Trp-Tyr-
Gly-Tyr-Thr-Pro-Gln-Asn-Val-Ile) as a tumor directing vector for the delivery of zinc (II) …

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