[HTML] Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket
DM Eckert, VN Malashkevich, LH Hong, PA Carr… - Cell, 1999 - Elsevier
Abstract The HIV-1 gp41 protein promotes viral entry by mediating the fusion of viral and
cellular membranes. A prominent pocket on the surface of a central trimeric coiled coil within
gp41 was previously identified as a potential target for drugs that inhibit HIV-1 entry. We
cellular membranes. A prominent pocket on the surface of a central trimeric coiled coil within
gp41 was previously identified as a potential target for drugs that inhibit HIV-1 entry. We
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