Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
DA Reardon, KL Fink, T Mikkelsen… - Journal of clinical …, 2008 - ascopubs.org
Purpose Cilengitide, an inhibitor of αvβ3 and αvβ5 integrin receptors, demonstrated minimal
toxicity and durable activity across a wide range of doses administered to adults with
recurrent glioblastoma multiforme (GBM) in a prior phase I study. The current multicenter
toxicity and durable activity across a wide range of doses administered to adults with
recurrent glioblastoma multiforme (GBM) in a prior phase I study. The current multicenter
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