Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans

Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans

C Wang, V Saar, KL Leung, L Chen, G Wong - Neurobiology of disease, 2018 - Elsevier

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
presence of extracellular amyloid plaques consisting of Amyloid-β peptide (Aβ) aggregates
and neurofibrillary tangles formed by aggregation of hyperphosphorylated microtubule …

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