2018年8月26日星期日

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

K Westerlund, M Altai, B Mitran… - Journal of Nuclear …, 2018 - diva-portal.org
Affibody molecules are small proteins engineered using a nonanti-body scaffold.
Radiolabeled Affibody molecules are excellent imaging probes, but their application to
radionuclide therapy has been prevented by high renal reabsorption. The aim of this study …


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