Product | CaMK-II (Thr305) Antibody |
Cat# | 100-32-77A |
Unit/Weight | 100 μg |
Unit Price | $381.00 |
Species Reactivity | B, Ck, D, H, M, X, Zf |
Tested Application(s) | E, WB |
Brief Description | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
Specific Description | CaM Kinase 2 alpha (CAMKII alpha) is a prominent Ser/Thr kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. A member of the NMDAR signaling complex at the excitatory synapse, it regulates NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. CAMK2a is composed of alpha, beta, gamma, and delta chains that assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. CaMK2a interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1. Phosphorylation of Thr286 produces an autonomously active form of CaM Kinase II. Autophosphorylation of Thr305 inhibits the activity CaM Kinase II. |
Storage | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
Peptide synthesis/Peptide Library Synthesis/Peptide Modification/Antibody Preparation Eve He eve@pepmic.com www.pepmic.com
2018年11月14日星期三
CaMK-II (Thr305) Antibody
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