CD22 (HIB22) Antibody

Product	CD22 (HIB22) Antibody
Cat#	100-30-36A
Unit/Weight	2 ml
Unit Price	$299.00
Species Reactivity	H
Tested Application(s)	FC
Brief Description	Mouse Monoclonal Antibody, PE-conjugated Antibody
Specific Description	The CD22 (HIB22) antibody recognizes a 130-140 kDa type-I transmembrane glycoprotein that is a B cell restricted antigen. CD22 antigen is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B lymphocytes. CD22 expression is increased after activation and lost at the terminal stage of B cell differentiation. Most B cell leukemias and lymphomas also express CD22. It is not expressed in T cells, monocytes and granulocytes. CD22 is an early marker for B-ALL and hairy-cell leukemia diagnostic. CD22 is an adhesion molecule that amplifies the signal of B cell activation. CD22 ligands are CD45RO antigen on T cells and CD75 antigen on B cells participating in the homotopic interaction of T and B cells.
Storage	Store at 4°C. Product is guaranteed 6 months from the date of shipment.