2018年11月14日星期三

Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin

Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin

SY Kim, F Zhang, W Gong, K Chen, K Xia, F Liu… - Journal of Biological …, 2018 - ASBMB
Phagocytic cells in fish secrete antimicrobial peptides (AMPs) such as piscidins,
glycosaminoglycans such as heparin, and copper ions as first-line immune defenses.
Recently, we established that Cu 2+ coordination by piscidins 1 (P1) and 3 (P3) enhances …


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