2018年11月22日星期四

Cytochrome‐P450‐Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs

Cytochrome‐P450‐Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs

C Barnaba, BR Sahoo, T Ravula… - Angewandte Chemie …, 2018 - Wiley Online Library
… In this study, we use peptide‐based lipid nanodiscs to “trap” the lipid boundaries of microsomal
cytochrome P450 2B4 … Peptide‐based nanodiscs have several advantages over membrane
scaffolding protein nanodiscs (MSP) for studying membrane proteins …


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