Development and in vitro Evaluation of Peptide-based Stealth Nanoparticles for Enzyme Replacement Therapy

Development and in vitro Evaluation of Peptide-based Stealth Nanoparticles for Enzyme Replacement Therapy

M Santi, A Cecchettini, G Maccari, S Luin… - 8th International …, 2017 - researchgate.net

Delivery of large therapeutic payloads to the central nervous system is challenging owing to
the presence of the blood brain barrier (BBB) that inhibits uptake of virtually any
macromolecule. Targeted nanostructures could overcome this issue, allowing delivery of …

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