2018年11月12日星期一

[HTML] Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

[HTML] Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

Z Song, RA Mansbach, H He, KC Shih… - Nature …, 2017 - nature.com
… similar to PA. One isostere of the peptide bond we were particularly interested in
studying was the 1,2,3-triazole group 30 , whose C5 hydrogen functions as the
H-bond donor and N3 acts as the acceptor (Fig. 2b). In analogy …


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